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Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9
Apoptosis in response to developmental cues and stress stimuli is mediated by caspases that are regulated by the Bcl-2 protein family. Although caspases 2 and 9 have each been proposed as the apical caspase in that pathway, neither is indispensable for the apoptosis of leukocytes or fibroblasts. To...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172407/ https://www.ncbi.nlm.nih.gov/pubmed/15210727 http://dx.doi.org/10.1083/jcb.200312030 |