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Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly

Primary cilia are nonmotile microtubule structures that assemble from basal bodies by a process called intraflagellar transport (IFT) and are associated with several human diseases. Here, we show that the centrosome protein pericentrin (Pcnt) colocalizes with IFT proteins to the base of primary and...

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Detalles Bibliográficos
Autores principales: Jurczyk, Agata, Gromley, Adam, Redick, Sambra, Agustin, Jovenal San, Witman, George, Pazour, Gregory J., Peters, Dorien J.M., Doxsey, Stephen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172416/
https://www.ncbi.nlm.nih.gov/pubmed/15337773
http://dx.doi.org/10.1083/jcb.200405023