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Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly
Primary cilia are nonmotile microtubule structures that assemble from basal bodies by a process called intraflagellar transport (IFT) and are associated with several human diseases. Here, we show that the centrosome protein pericentrin (Pcnt) colocalizes with IFT proteins to the base of primary and...
Autores principales: | Jurczyk, Agata, Gromley, Adam, Redick, Sambra, Agustin, Jovenal San, Witman, George, Pazour, Gregory J., Peters, Dorien J.M., Doxsey, Stephen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172416/ https://www.ncbi.nlm.nih.gov/pubmed/15337773 http://dx.doi.org/10.1083/jcb.200405023 |
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