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Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation

The epidermal growth factor (EGF)–induced increase in free barbed ends, resulting in actin polymerization at the leading edge of the lamellipodium in carcinoma cells, occurs as two transients: an early one at 1 min and a late one at 3 min. Our results reveal that phospholipase (PLC) is required for...

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Detalles Bibliográficos
Autores principales: Mouneimne, Ghassan, Soon, Lilian, DesMarais, Vera, Sidani, Mazen, Song, Xiaoyan, Yip, Shu-Chin, Ghosh, Mousumi, Eddy, Robert, Backer, Jonathan M., Condeelis, John
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172433/
https://www.ncbi.nlm.nih.gov/pubmed/15337778
http://dx.doi.org/10.1083/jcb.200405156