Sorting of a nonmuscle tropomyosin to a novel cytoskeletal compartment in skeletal muscle results in muscular dystrophy

Tropomyosin (Tm) is a key component of the actin cytoskeleton and >40 isoforms have been described in mammals. In addition to the isoforms in the sarcomere, we now report the existence of two nonsarcomeric (NS) isoforms in skeletal muscle. These isoforms are excluded from the thin filament of the...

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Detalles Bibliográficos
Autores principales: Kee, Anthony J., Schevzov, Galina, Nair-Shalliker, Visalini, Robinson, C. Stephen, Vrhovski, Bernadette, Ghoddusi, Majid, Qiu, Min Ru, Lin, Jim J.-C., Weinberger, Ron, Gunning, Peter W., Hardeman, Edna C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172434/
https://www.ncbi.nlm.nih.gov/pubmed/15337777
http://dx.doi.org/10.1083/jcb.200406181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172434/
https://www.ncbi.nlm.nih.gov/pubmed/15337777
http://dx.doi.org/10.1083/jcb.200406181

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