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Sorting of a nonmuscle tropomyosin to a novel cytoskeletal compartment in skeletal muscle results in muscular dystrophy
Tropomyosin (Tm) is a key component of the actin cytoskeleton and >40 isoforms have been described in mammals. In addition to the isoforms in the sarcomere, we now report the existence of two nonsarcomeric (NS) isoforms in skeletal muscle. These isoforms are excluded from the thin filament of the...
Autores principales: | Kee, Anthony J., Schevzov, Galina, Nair-Shalliker, Visalini, Robinson, C. Stephen, Vrhovski, Bernadette, Ghoddusi, Majid, Qiu, Min Ru, Lin, Jim J.-C., Weinberger, Ron, Gunning, Peter W., Hardeman, Edna C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172434/ https://www.ncbi.nlm.nih.gov/pubmed/15337777 http://dx.doi.org/10.1083/jcb.200406181 |
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