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The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells

In Drosophila, activation of the apical caspase DRONC requires the apoptotic protease-activating factor homologue, DARK. However, unlike caspase activation in mammals, DRONC activation is not accompanied by the release of cytochrome c from mitochondria. Drosophila encodes two cytochrome c proteins,...

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Detalles Bibliográficos
Autores principales: Dorstyn, Loretta, Mills, Kathryn, Lazebnik, Yuri, Kumar, Sharad
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172470/
https://www.ncbi.nlm.nih.gov/pubmed/15533997
http://dx.doi.org/10.1083/jcb.200408054