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The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells
In Drosophila, activation of the apical caspase DRONC requires the apoptotic protease-activating factor homologue, DARK. However, unlike caspase activation in mammals, DRONC activation is not accompanied by the release of cytochrome c from mitochondria. Drosophila encodes two cytochrome c proteins,...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172470/ https://www.ncbi.nlm.nih.gov/pubmed/15533997 http://dx.doi.org/10.1083/jcb.200408054 |