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A pRb-independent mechanism preserves the postmitotic state in terminally differentiated skeletal muscle cells

In skeletal muscle differentiation, the retinoblastoma protein (pRb) is absolutely necessary to establish definitive mitotic arrest. It is widely assumed that pRb is equally essential to sustain the postmitotic state, but this contention has never been tested. Here, we show that terminal proliferati...

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Detalles Bibliográficos
Autores principales: Camarda, Grazia, Siepi, Francesca, Pajalunga, Deborah, Bernardini, Camilla, Rossi, Rossella, Montecucco, Alessandra, Meccia, Ettore, Crescenzi, Marco
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172476/
https://www.ncbi.nlm.nih.gov/pubmed/15520231
http://dx.doi.org/10.1083/jcb.200408164