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A pRb-independent mechanism preserves the postmitotic state in terminally differentiated skeletal muscle cells
In skeletal muscle differentiation, the retinoblastoma protein (pRb) is absolutely necessary to establish definitive mitotic arrest. It is widely assumed that pRb is equally essential to sustain the postmitotic state, but this contention has never been tested. Here, we show that terminal proliferati...
Autores principales: | Camarda, Grazia, Siepi, Francesca, Pajalunga, Deborah, Bernardini, Camilla, Rossi, Rossella, Montecucco, Alessandra, Meccia, Ettore, Crescenzi, Marco |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172476/ https://www.ncbi.nlm.nih.gov/pubmed/15520231 http://dx.doi.org/10.1083/jcb.200408164 |
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