The 4q subtelomere harboring the FSHD locus is specifically anchored with peripheral heterochromatin unlike most human telomeres

This paper investigates the nuclear localization of human telomeres and, specifically, the 4q35 subtelomere mutated in facioscapulohumeral dystrophy (FSHD). FSHD is a common muscular dystrophy that has been linked to contraction of D4Z4 tandem repeats, widely postulated to affect distant gene expres...

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Detalles Bibliográficos
Autores principales: Tam, Rose, Smith, Kelly P., Lawrence, Jeanne B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172553/
https://www.ncbi.nlm.nih.gov/pubmed/15504910
http://dx.doi.org/10.1083/jcb.200403128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172553/
https://www.ncbi.nlm.nih.gov/pubmed/15504910
http://dx.doi.org/10.1083/jcb.200403128

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