Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis

Despite the potential of the inhibitor of apoptosis proteins (IAPs) to block cytochrome c–dependent caspase activation, the critical function of IAPs in regulating mammalian apoptosis remains unclear. We report that the ability of endogenous IAPs to effectively regulate caspase activation depends on...

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Detalles Bibliográficos
Autores principales: Wright, Kevin M., Linhoff, Michael W., Potts, Patrick Ryan, Deshmukh, Mohanish
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172554/
https://www.ncbi.nlm.nih.gov/pubmed/15504912
http://dx.doi.org/10.1083/jcb.200406073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172554/
https://www.ncbi.nlm.nih.gov/pubmed/15504912
http://dx.doi.org/10.1083/jcb.200406073

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