Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival

The Pit1-Oct1-Unc86 domain (POU domain) transcription factor Brn3a controls sensory neuron survival by regulating the expression of Trk receptors and members of the Bcl-2 family. Loss of Brn3a leads to a dramatic increase in apoptosis and severe loss of neurons in sensory ganglia. Although recent ev...

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Detalles Bibliográficos
Autores principales: Wiggins, Amanda K., Wei, Guangwei, Doxakis, Epaminondas, Wong, Connie, Tang, Amy A., Zang, Keling, Luo, Esther J., Neve, Rachael L., Reichardt, Louis F., Huang, Eric J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172556/
https://www.ncbi.nlm.nih.gov/pubmed/15492043
http://dx.doi.org/10.1083/jcb.200406131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172556/
https://www.ncbi.nlm.nih.gov/pubmed/15492043
http://dx.doi.org/10.1083/jcb.200406131

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