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Mlp-dependent anchorage and stabilization of a desumoylating enzyme is required to prevent clonal lethality

Myosin-like proteins 1 and 2 (Mlp1 and Mlp2) form filaments attached to the nucleoplasmic side of the nuclear pore complexes via interaction with the nucleoporin Nup60. Here, we show that Mlps and Nup60, but not several other nucleoporins, are required to localize and stabilize a desumoylating enzym...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaolan, Wu, Chia-Yung, Blobel, Günter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172573/
https://www.ncbi.nlm.nih.gov/pubmed/15557117
http://dx.doi.org/10.1083/jcb.200405168