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Mlp-dependent anchorage and stabilization of a desumoylating enzyme is required to prevent clonal lethality
Myosin-like proteins 1 and 2 (Mlp1 and Mlp2) form filaments attached to the nucleoplasmic side of the nuclear pore complexes via interaction with the nucleoporin Nup60. Here, we show that Mlps and Nup60, but not several other nucleoporins, are required to localize and stabilize a desumoylating enzym...
Autores principales: | Zhao, Xiaolan, Wu, Chia-Yung, Blobel, Günter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172573/ https://www.ncbi.nlm.nih.gov/pubmed/15557117 http://dx.doi.org/10.1083/jcb.200405168 |
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