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Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance

Netrin-1 acts as a chemoattractant molecule to guide commissural neurons (CN) toward the floor plate by interacting with the receptor deleted in colorectal cancer (DCC). The molecular mechanisms underlying Netrin-1–DCC signaling are still poorly characterized. Here, we show that DCC is phosphorylate...

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Detalles Bibliográficos
Autores principales: Meriane, Mayya, Tcherkezian, Joseph, Webber, Christine A., Danek, Eric I., Triki, Ibtissem, McFarlane, Sarah, Bloch-Gallego, Evelyne, Lamarche-Vane, Nathalie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172574/
https://www.ncbi.nlm.nih.gov/pubmed/15557120
http://dx.doi.org/10.1083/jcb.200405053