Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell–derived neural transplants

The formation of stem cell–derived tumors (teratomas) is observed when engrafting undifferentiated embryonic stem (ES) cells, embryoid body–derived cells (EBCs), or mammalian embryos and is a significant obstacle to stem cell therapy. We show that in tumors formed after engraftment of EBCs into mous...

Descripción completa

Detalles Bibliográficos
Autores principales: Bieberich, Erhard, Silva, Jeane, Wang, Guanghu, Krishnamurthy, Kannan, Condie, Brian G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172580/
https://www.ncbi.nlm.nih.gov/pubmed/15545317
http://dx.doi.org/10.1083/jcb.200405144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172580/
https://www.ncbi.nlm.nih.gov/pubmed/15545317
http://dx.doi.org/10.1083/jcb.200405144

Ejemplares similares