Cargando…
Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell–derived neural transplants
The formation of stem cell–derived tumors (teratomas) is observed when engrafting undifferentiated embryonic stem (ES) cells, embryoid body–derived cells (EBCs), or mammalian embryos and is a significant obstacle to stem cell therapy. We show that in tumors formed after engraftment of EBCs into mous...
Autores principales: | Bieberich, Erhard, Silva, Jeane, Wang, Guanghu, Krishnamurthy, Kannan, Condie, Brian G. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2004
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172580/ https://www.ncbi.nlm.nih.gov/pubmed/15545317 http://dx.doi.org/10.1083/jcb.200405144 |
Ejemplares similares
-
Deoxycholate promotes survival of breast cancer cells by reducing the level of pro-apoptotic ceramide
por: Krishnamurthy, Kannan, et al.
Publicado: (2008) -
Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide
por: Bieberich, Erhard, et al.
Publicado: (2003) -
Characterization of an apical ceramide-enriched compartment regulating ciliogenesis
por: He, Qian, et al.
Publicado: (2012) -
Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide
por: He, Qian, et al.
Publicado: (2014) -
Association of Aβ with ceramide-enriched astrosomes mediates Aβ neurotoxicity
por: Elsherbini, Ahmed, et al.
Publicado: (2020)