Integrin αv-mediated inactivation of p53 controls a MEK1-dependent melanoma cell survival pathway in three-dimensional collagen

Integrin αv is required for melanoma cell survival and tumor growth in various models. To elucidate integrin αv-mediated melanoma cell survival mechanisms, we used a three-dimensional (3D) collagen gel model mimicking the pathophysiological microenvironment of malignant melanoma in the dermis. We fo...

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Detalles Bibliográficos
Autores principales: Bao, Wenjie, Strömblad, Staffan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172581/
https://www.ncbi.nlm.nih.gov/pubmed/15557124
http://dx.doi.org/10.1083/jcb.200404018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172581/
https://www.ncbi.nlm.nih.gov/pubmed/15557124
http://dx.doi.org/10.1083/jcb.200404018

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