Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import

Ubiquitin is a small polypeptide that is conjugated to proteins and commonly serves as a degradation signal. The attachment of ubiquitin (Ub) to a substrate proceeds through a multi-enzyme cascade involving an activating enzyme (E1), a conjugating enzyme (E2), and a protein ligase (E3). We previousl...

Descripción completa

Detalles Bibliográficos
Autores principales: Plafker, Scott M., Plafker, Kendra S., Weissman, Allan M., Macara, Ian G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172591/
https://www.ncbi.nlm.nih.gov/pubmed/15545318
http://dx.doi.org/10.1083/jcb.200406001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172591/
https://www.ncbi.nlm.nih.gov/pubmed/15545318
http://dx.doi.org/10.1083/jcb.200406001

Ejemplares similares