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Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import
Ubiquitin is a small polypeptide that is conjugated to proteins and commonly serves as a degradation signal. The attachment of ubiquitin (Ub) to a substrate proceeds through a multi-enzyme cascade involving an activating enzyme (E1), a conjugating enzyme (E2), and a protein ligase (E3). We previousl...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172591/ https://www.ncbi.nlm.nih.gov/pubmed/15545318 http://dx.doi.org/10.1083/jcb.200406001 |