SPOTS: signaling protein oligomeric transduction structures are early mediators of death receptor–induced apoptosis at the plasma membrane

Fas (CD95, APO-1, TNFRSF6) is a TNF receptor superfamily member that directly triggers apoptosis and contributes to the maintenance of lymphocyte homeostasis and prevention of autoimmunity. Although FADD and caspase-8 have been identified as key intracellular mediators of Fas signaling, it is not cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Siegel, Richard M., Muppidi, Jagan R., Sarker, Malabika, Lobito, Adrian, Jen, Melinda, Martin, David, Straus, Stephen E., Lenardo, Michael J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172594/
https://www.ncbi.nlm.nih.gov/pubmed/15557123
http://dx.doi.org/10.1083/jcb.200406101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172594/
https://www.ncbi.nlm.nih.gov/pubmed/15557123
http://dx.doi.org/10.1083/jcb.200406101

Ejemplares similares