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Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex

Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs) whose complex architecture is generated from a set of only ∼30 proteins, termed nucleoporins. Here, we explore the domain structure of Nup133, a nucleoporin in a conserved NPC subcomplex that is crucial for NPC biogenesis and i...

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Detalles Bibliográficos
Autores principales: Berke, Ian C., Boehmer, Thomas, Blobel, Günter, Schwartz, Thomas U.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172596/
https://www.ncbi.nlm.nih.gov/pubmed/15557116
http://dx.doi.org/10.1083/jcb.200408109