TSC2 modulates actin cytoskeleton and focal adhesion through TSC1-binding domain and the Rac1 GTPase

Tuberous sclerosis complex (TSC) 1 and TSC2 are thought to be involved in protein translational regulation and cell growth, and loss of their function is a cause of TSC and lymphangioleiomyomatosis (LAM). However, TSC1 also activates Rho and regulates cell adhesion. We found that TSC2 modulates acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Goncharova, Elena, Goncharov, Dmitry, Noonan, Daniel, Krymskaya, Vera P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172598/
https://www.ncbi.nlm.nih.gov/pubmed/15611338
http://dx.doi.org/10.1083/jcb.200405130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172598/
https://www.ncbi.nlm.nih.gov/pubmed/15611338
http://dx.doi.org/10.1083/jcb.200405130

Ejemplares similares