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Processive capping by formin suggests a force-driven mechanism of actin polymerization

Regulation of actin polymerization is essential for cell functioning. Here, we predict a novel phenomenon—the force-driven polymerization of actin filaments mediated by proteins of the formin family. Formins localize to the barbed ends of actin filaments, but, in contrast to the standard capping pro...

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Detalles Bibliográficos
Autores principales: Kozlov, Michael M., Bershadsky, Alexander D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172604/
https://www.ncbi.nlm.nih.gov/pubmed/15596547
http://dx.doi.org/10.1083/jcb.200410017