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Force measurements in E-cadherin–mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42

We have used a modified, dual pipette assay to quantify the strength of cadherin-dependent cell–cell adhesion. The force required to separate E-cadherin–expressing paired cells in suspension was measured as an index of intercellular adhesion. Separation force depended on the homophilic interaction o...

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Detalles Bibliográficos
Autores principales: Chu, Yeh-Shiu, Thomas, William A., Eder, Olivier, Pincet, Frederic, Perez, Eric, Thiery, Jean Paul, Dufour, Sylvie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172605/
https://www.ncbi.nlm.nih.gov/pubmed/15596540
http://dx.doi.org/10.1083/jcb.200403043