Palmitoylation supports assembly and function of integrin–tetraspanin complexes

As observed previously, tetraspanin palmitoylation promotes tetraspanin microdomain assembly. Here, we show that palmitoylated integrins (α3, α6, and β4 subunits) and tetraspanins (CD9, CD81, and CD63) coexist in substantially overlapping complexes. Removal of β4 palmitoylation sites markedly impair...

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Detalles Bibliográficos
Autores principales: Yang, Xiuwei, Kovalenko, Oleg V., Tang, Wei, Claas, Christoph, Stipp, Christopher S., Hemler, Martin E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172609/
https://www.ncbi.nlm.nih.gov/pubmed/15611341
http://dx.doi.org/10.1083/jcb.200404100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172609/
https://www.ncbi.nlm.nih.gov/pubmed/15611341
http://dx.doi.org/10.1083/jcb.200404100

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