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Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble

Cell polarity and cell proliferation can be coupled in animal tissues, but how they are coupled is not understood. In Drosophila imaginal discs, loss of the neoplastic tumor suppressor gene scribble (scrib), which encodes a multidomain scaffolding protein, disrupts epithelial organization and also c...

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Detalles Bibliográficos
Autores principales: Zeitler, Jennifer, Hsu, Cynthia P., Dionne, Heather, Bilder, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172630/
https://www.ncbi.nlm.nih.gov/pubmed/15611336
http://dx.doi.org/10.1083/jcb.200407158