Compensation mechanism in tumor cell migration: mesenchymal–amoeboid transition after blocking of pericellular proteolysis

Invasive tumor dissemination in vitro and in vivo involves the proteolytic degradation of ECM barriers. This process, however, is only incompletely attenuated by protease inhibitor–based treatment, suggesting the existence of migratory compensation strategies. In three-dimensional collagen matrices,...

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Detalles Bibliográficos
Autores principales: Wolf, Katarina, Mazo, Irina, Leung, Harry, Engelke, Katharina, von Andrian, Ulrich H., Deryugina, Elena I., Strongin, Alex Y., Bröcker, Eva-B., Friedl, Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172637/
https://www.ncbi.nlm.nih.gov/pubmed/12527751
http://dx.doi.org/10.1083/jcb.200209006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172637/
https://www.ncbi.nlm.nih.gov/pubmed/12527751
http://dx.doi.org/10.1083/jcb.200209006

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