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Direct visualization of Ras proteins in spatially distinct cell surface microdomains

Localization of signaling complexes to specific microdomains coordinates signal transduction at the plasma membrane. Using immunogold electron microscopy of plasma membrane sheets coupled with spatial point pattern analysis, we have visualized morphologically featureless microdomains, including lipi...

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Detalles Bibliográficos
Autores principales: Prior, Ian A., Muncke, Cornelia, Parton, Robert G., Hancock, John F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172642/
https://www.ncbi.nlm.nih.gov/pubmed/12527752
http://dx.doi.org/10.1083/jcb.200209091