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Direct visualization of Ras proteins in spatially distinct cell surface microdomains
Localization of signaling complexes to specific microdomains coordinates signal transduction at the plasma membrane. Using immunogold electron microscopy of plasma membrane sheets coupled with spatial point pattern analysis, we have visualized morphologically featureless microdomains, including lipi...
Autores principales: | Prior, Ian A., Muncke, Cornelia, Parton, Robert G., Hancock, John F. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172642/ https://www.ncbi.nlm.nih.gov/pubmed/12527752 http://dx.doi.org/10.1083/jcb.200209091 |
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