Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

Mitochondrial morphology is determined by a dynamic equilibrium between organelle fusion and fission, but the significance of these processes in vertebrates is unknown. The mitofusins, Mfn1 and Mfn2, have been shown to affect mitochondrial morphology when overexpressed. We find that mice deficient i...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hsiuchen, Detmer, Scott A., Ewald, Andrew J., Griffin, Erik E., Fraser, Scott E., Chan, David C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172648/
https://www.ncbi.nlm.nih.gov/pubmed/12527753
http://dx.doi.org/10.1083/jcb.200211046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172648/
https://www.ncbi.nlm.nih.gov/pubmed/12527753
http://dx.doi.org/10.1083/jcb.200211046

Ejemplares similares