Cargando…

The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast

During mitosis in Saccharomyces cerevisiae, the mitotic spindle moves into the mother–bud neck via dynein-dependent sliding of cytoplasmic microtubules along the cortex of the bud. Here we show that Pac1, the yeast homologue of the human lissencephaly protein LIS1, plays a key role in this process....

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Wei-Lih, Oberle, Jessica R., Cooper, John A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172672/
https://www.ncbi.nlm.nih.gov/pubmed/12566428
http://dx.doi.org/10.1083/jcb.200209022