Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation

The WD-repeat proteins Rae1 and Bub3 show extensive sequence homology, indicative of functional similarity. However, previous studies have suggested that Rae1 is involved in the mRNA export pathway and Bub3 in the mitotic checkpoint. To determine the in vivo roles of Rae1 and Bub3 in mammals, we gen...

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Detalles Bibliográficos
Autores principales: Babu, J. Ramesh, Jeganathan, Karthik B., Baker, Darren J., Wu, Xiaosheng, Kang-Decker, Ningling, van Deursen, Jan M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172680/
https://www.ncbi.nlm.nih.gov/pubmed/12551952
http://dx.doi.org/10.1083/jcb.200211048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172680/
https://www.ncbi.nlm.nih.gov/pubmed/12551952
http://dx.doi.org/10.1083/jcb.200211048

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