Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics

Microtubule plus ends dynamically attach to kinetochores on mitotic chromosomes. We directly imaged this dynamic interface using high resolution fluorescent speckle microscopy and direct labeling of kinetochores in Xenopus extract spindles. During metaphase, kinetochores were stationary and under te...

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Detalles Bibliográficos
Autores principales: Maddox, Paul, Straight, Aaron, Coughlin, Peg, Mitchison, Timothy J., Salmon, Edward D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172681/
https://www.ncbi.nlm.nih.gov/pubmed/12900391
http://dx.doi.org/10.1083/jcb.200301088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172681/
https://www.ncbi.nlm.nih.gov/pubmed/12900391
http://dx.doi.org/10.1083/jcb.200301088

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