Engineered chromosome regions with altered sequence composition demonstrate hierarchical large-scale folding within metaphase chromosomes

Mitotic chromosome structure and DNA sequence requirements for normal chromosomal condensation remain unknown. We engineered labeled chromosome regions with altered scaffold-associated region (SAR) sequence composition as a formal test of the radial loop and other chromosome models. Chinese hamster...

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Detalles Bibliográficos
Autores principales: Strukov, Yuri G., Wang, Yan, Belmont, Andrew S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172725/
https://www.ncbi.nlm.nih.gov/pubmed/12835314
http://dx.doi.org/10.1083/jcb.200303098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172725/
https://www.ncbi.nlm.nih.gov/pubmed/12835314
http://dx.doi.org/10.1083/jcb.200303098

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