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Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes

Chondrocyte proliferation and differentiation requires their attachment to the collagen type II–rich matrix of developing bone. This interaction is mediated by integrins and their cytoplasmic effectors, such as the integrin-linked kinase (ILK). To elucidate the molecular mechanisms whereby integrins...

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Detalles Bibliográficos
Autores principales: Terpstra, Leonieke, Prud'homme, Josée, Arabian, Alice, Takeda, Shu, Karsenty, Gérard, Dedhar, Shoukat, St-Arnaud, René
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172728/
https://www.ncbi.nlm.nih.gov/pubmed/12835312
http://dx.doi.org/10.1083/jcb.200302066