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Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes
Chondrocyte proliferation and differentiation requires their attachment to the collagen type II–rich matrix of developing bone. This interaction is mediated by integrins and their cytoplasmic effectors, such as the integrin-linked kinase (ILK). To elucidate the molecular mechanisms whereby integrins...
Autores principales: | Terpstra, Leonieke, Prud'homme, Josée, Arabian, Alice, Takeda, Shu, Karsenty, Gérard, Dedhar, Shoukat, St-Arnaud, René |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172728/ https://www.ncbi.nlm.nih.gov/pubmed/12835312 http://dx.doi.org/10.1083/jcb.200302066 |
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