Characterization of the signal that directs Bcl-x(L), but not Bcl-2, to the mitochondrial outer membrane

It is assumed that the survival factors Bcl-2 and Bcl-x(L) are mainly functional on mitochondria and therefore must contain mitochondrial targeting sequences. Here we show, however, that only Bcl-x(L) is specifically targeted to the mitochondrial outer membrane (MOM) whereas Bcl-2 distributes on sev...

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Detalles Bibliográficos
Autores principales: Kaufmann, Thomas, Schlipf, Sarah, Sanz, Javier, Neubert, Karin, Stein, Reuven, Borner, Christoph
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172731/
https://www.ncbi.nlm.nih.gov/pubmed/12515824
http://dx.doi.org/10.1083/jcb.200210084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172731/
https://www.ncbi.nlm.nih.gov/pubmed/12515824
http://dx.doi.org/10.1083/jcb.200210084

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