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PTPα regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration

We investigated the molecular and cellular actions of receptor protein tyrosine phosphatase (PTP) α in integrin signaling using immortalized fibroblasts derived from wild-type and PTPα-deficient mouse embryos. Defects in PTPα(−/−) migration in a wound healing assay were associated with altered cell...

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Detalles Bibliográficos
Autores principales: Zeng, Li, Si, Xiaoning, Yu, Wei-Ping, Le, Hoa Thi, Ng, Kwok Peng, Teng, Raymond M.H., Ryan, Kenneth, Wang, Dennis Z.-M., Ponniah, Sathivel, Pallen, Catherine J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172736/
https://www.ncbi.nlm.nih.gov/pubmed/12515828
http://dx.doi.org/10.1083/jcb.200206049