Cargando…

PTPα regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration

We investigated the molecular and cellular actions of receptor protein tyrosine phosphatase (PTP) α in integrin signaling using immortalized fibroblasts derived from wild-type and PTPα-deficient mouse embryos. Defects in PTPα(−/−) migration in a wound healing assay were associated with altered cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Li, Si, Xiaoning, Yu, Wei-Ping, Le, Hoa Thi, Ng, Kwok Peng, Teng, Raymond M.H., Ryan, Kenneth, Wang, Dennis Z.-M., Ponniah, Sathivel, Pallen, Catherine J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172736/ https://www.ncbi.nlm.nih.gov/pubmed/12515828 http://dx.doi.org/10.1083/jcb.200206049

Ejemplares similares

β Integrins Mediate FAK Y397 Autophosphorylation of Resistance Arteries during Eutrophic Inward Remodeling in Hypertension
por: Heerkens, Egidius H.J, et al.
Publicado: (2014)

Porcine Hemagglutinating Encephalomyelitis Virus Activation of the Integrin α5β1-FAK-Cofilin Pathway Causes Cytoskeletal Rearrangement To Promote Its Invasion of N2a Cells
por: Lv, Xiaoling, et al.
Publicado: (2019)

PTP-1B is an essential positive regulator of platelet integrin signaling
por: Arias-Salgado, Elena Garcia, et al.
Publicado: (2005)

Integrin and FAK Regulation of Human Pluripotent Stem Cells
por: Vitillo, Loriana, et al.
Publicado: (2017)

Molecular Mechanisms of Host Cytoskeletal Rearrangements by Shigella Invasins
por: Lee, Jun Hyuck, et al.
Publicado: (2014)

Autophosphorylation and the Dynamics of the Activation of Lck
por: Kreusser, Lisa Maria, et al.
Publicado: (2021)

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules
Publicado: (1995)

FAK and talin: Who is taking whom to the integrin engagement party?
por: Serrels, Bryan, et al.
Publicado: (2012)

Graphene-Induced Osteogenic Differentiation Is Mediated by the Integrin/FAK Axis
por: Xie, Han, et al.
Publicado: (2019)

Plectin protects podocytes from adriamycin‐induced apoptosis and F‐actin cytoskeletal disruption through the integrin α6β4/FAK/p38 MAPK pathway
por: Ni, Yongliang, et al.
Publicado: (2018)

Integrin-cytoskeletal interactions in migrating fibroblasts are dynamic, asymmetric, and regulated
Publicado: (1993)

Structural and biophysical properties of the integrin-associated cytoskeletal protein talin
por: Roberts, Gordon C. K., et al.
Publicado: (2009)

Integrin-mediated Activation of MAP Kinase Is Independent of FAK: Evidence for Dual Integrin Signaling Pathways in Fibroblasts
por: Lin, Tsung H., et al.
Publicado: (1997)

Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway
por: Huang, Chun-Yung, et al.
Publicado: (2009)

LOXL2 attenuates osteoarthritis through inactivating Integrin/FAK signaling
por: Zhang, Caixia, et al.
Publicado: (2021)

Clutching at Guidance Cues: The Integrin–FAK Axis Steers Axon Outgrowth
por: Davis-Lunn, Mathew, et al.
Publicado: (2023)

Data on evolution of intrinsically disordered regions of the human kinome and contribution of FAK1 IDRs to cytoskeletal remodeling
por: Kathiriya, Jaymin J., et al.
Publicado: (2016)

Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

PTP1B triggers integrin-mediated repression of myosin activity and modulates cell contractility
por: González Wusener, Ana E., et al.
Publicado: (2015)

Interactions of the Mechanosensitive Channels with Extracellular Matrix, Integrins, and Cytoskeletal Network in Osmosensation
por: Jiao, Runsheng, et al.
Publicado: (2017)

TREK-1 Regulates Cytokine Secretion from Cultured Human Alveolar Epithelial Cells Independently of Cytoskeletal Rearrangements
por: Schwingshackl, Andreas, et al.
Publicado: (2015)

NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer
por: Yan, Hongfei, et al.
Publicado: (2019)

Modulation of cell migration by integrin-mediated cytoskeletal linkages and ligand-binding affinity
Publicado: (1996)

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly
Publicado: (1992)

Regulation of Response Regulator Autophosphorylation through Interdomain Contacts
por: Barbieri, Christopher M., et al.
Publicado: (2010)

Autophosphorylation and Self-Activation of DNA-Dependent Protein Kinase
por: Kurosawa, Aya
Publicado: (2021)

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets
Publicado: (1992)

Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2016)

NPTX1 Promotes Metastasis via Integrin/FAK Signaling in Gastric Cancer [Retraction]
Publicado: (2023)

Cytoskeletal Rearrangements in Synovial Fibroblasts as a Novel Pathophysiological Determinant of Modeled Rheumatoid Arthritis
por: Aidinis, Vassilis, et al.
Publicado: (2005)

RAF dimers control vascular permeability and cytoskeletal rearrangements at endothelial cell‐cell junctions
por: Dorard, Coralie, et al.
Publicado: (2019)

Massive elimination of multinucleated osteoclasts by eupatilin is due to dual inhibition of transcription and cytoskeletal rearrangement
por: Kim, Ju-Young, et al.
Publicado: (2015)

TRPV4 Promotes Metastasis in Melanoma by Regulating Cell Motility through Cytoskeletal Rearrangement
por: Huang, Shuai, et al.
Publicado: (2022)

Angiopoietin-Like 3 Induces Podocyte F-Actin Rearrangement through Integrin α (V) β (3)/FAK/PI3K Pathway-Mediated Rac1 Activation
por: Lin, Yi, et al.
Publicado: (2013)

Impaired Integrin-mediated Adhesion and Signaling in Fibroblasts Expressing a Dominant-negative Mutant PTP1B
por: Arregui, Carlos O., et al.
Publicado: (1998)

An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer
por: Tai, Yu-Ling, et al.
Publicado: (2015)

Inhibition of the integrin/FAK signaling axis and c-Myc synergistically disrupts ovarian cancer malignancy
por: Xu, B, et al.
Publicado: (2017)

IL-32γ attenuates airway fibrosis by modulating the integrin-FAK signaling pathway in fibroblasts
por: Hong, Gyong Hwa, et al.
Publicado: (2018)

Erratum to: Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2017)

Correction to: Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qtq7ski678eao8oi9tc2tjvu2b