Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

Stimulation of cell surface death receptors activates caspase-8, which targets a limited number of substrates including BAP31, an integral membrane protein of the endoplasmic reticulum (ER). Recently, we reported that a caspase-resistant BAP31 mutant inhibited several features of Fas-induced apoptos...

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Detalles Bibliográficos
Autores principales: Breckenridge, David G., Stojanovic, Marina, Marcellus, Richard C., Shore, Gordon C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172754/
https://www.ncbi.nlm.nih.gov/pubmed/12668660
http://dx.doi.org/10.1083/jcb.200212059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172754/
https://www.ncbi.nlm.nih.gov/pubmed/12668660
http://dx.doi.org/10.1083/jcb.200212059

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