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An essential role for hGle1 nucleocytoplasmic shuttling in mRNA export

Gle1 is required for mRNA export in yeast and human cells. Here, we report that two human Gle1 (hGle1) isoforms are expressed in HeLa cells (hGle1A and B). The two encoded proteins are identical except for their COOH-terminal regions. hGle1A ends with a unique four–amino acid segment, whereas hGle1B...

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Detalles Bibliográficos
Autores principales: Kendirgi, Frederic, Barry, Dianne M., Griffis, Eric R., Powers, Maureen A., Wente, Susan R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172758/
https://www.ncbi.nlm.nih.gov/pubmed/12668658
http://dx.doi.org/10.1083/jcb.200211081