Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response

Anumber of proteins are recruited to nuclear foci upon exposure to double-strand DNA damage, including 53BP1 and Rad51, but the precise role of these DNA damage–induced foci remain unclear. Here we show in a variety of human cell lines that histone deacetylase (HDAC) 4 is recruited to foci with kine...

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Detalles Bibliográficos
Autores principales: Kao, Gary D., McKenna, W. Gillies, Guenther, Matthew G., Muschel, Ruth J., Lazar, Mitchell A., Yen, Tim J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172769/
https://www.ncbi.nlm.nih.gov/pubmed/12668657
http://dx.doi.org/10.1083/jcb.200209065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172769/
https://www.ncbi.nlm.nih.gov/pubmed/12668657
http://dx.doi.org/10.1083/jcb.200209065

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