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Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response
Anumber of proteins are recruited to nuclear foci upon exposure to double-strand DNA damage, including 53BP1 and Rad51, but the precise role of these DNA damage–induced foci remain unclear. Here we show in a variety of human cell lines that histone deacetylase (HDAC) 4 is recruited to foci with kine...
Autores principales: | Kao, Gary D., McKenna, W. Gillies, Guenther, Matthew G., Muschel, Ruth J., Lazar, Mitchell A., Yen, Tim J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172769/ https://www.ncbi.nlm.nih.gov/pubmed/12668657 http://dx.doi.org/10.1083/jcb.200209065 |
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