Epstein-Barr virus LMP1 blocks p16(INK4a)–RB pathway by promoting nuclear export of E2F4/5

The p16(INK4a)–RB pathway plays a critical role in preventing inappropriate cell proliferation and is often targeted by viral oncoproteins during immortalization. Latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) is often present in EBV-associated proliferative diseases and is critical fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohtani, Naoko, Brennan, Paul, Gaubatz, Stefan, Sanij, Elaine, Hertzog, Paul, Wolvetang, Ernst, Ghysdael, Jacques, Rowe, Martin, Hara, Eiji
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172795/
https://www.ncbi.nlm.nih.gov/pubmed/12860972
http://dx.doi.org/10.1083/jcb.200302085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172795/
https://www.ncbi.nlm.nih.gov/pubmed/12860972
http://dx.doi.org/10.1083/jcb.200302085

Ejemplares similares