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Critical roles for the COOH-terminal NITY and RGT sequences of the integrin β(3) cytoplasmic domain in inside-out and outside-in signaling

Bidirectional signaling of integrin α(IIb)β(3) requires the β(3) cytoplasmic domain. To determine the sequence in the β(3) cytoplasmic domain that is critical to integrin signaling, cell lines were established that coexpress the platelet receptor for von Willebrand factor (vWF), glycoprotein Ib-IX,...

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Detalles Bibliográficos
Autores principales: Xi, Xiaodong, Bodnar, Richard J., Li, Zhenyu, Lam, Stephen C.-T., Du, Xiaoping
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172800/
https://www.ncbi.nlm.nih.gov/pubmed/12860973
http://dx.doi.org/10.1083/jcb.200303120