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Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system

Growth inhibitory proteins in the central nervous system (CNS) block axon growth and regeneration by signaling to Rho, an intracellular GTPase. It is not known how CNS trauma affects the expression and activation of RhoA. Here we detect GTP-bound RhoA in spinal cord homogenates and report that spina...

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Detalles Bibliográficos
Autores principales: Dubreuil, Catherine I., Winton, Matthew J., McKerracher, Lisa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172802/
https://www.ncbi.nlm.nih.gov/pubmed/12860969
http://dx.doi.org/10.1083/jcb.200301080