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Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system
Growth inhibitory proteins in the central nervous system (CNS) block axon growth and regeneration by signaling to Rho, an intracellular GTPase. It is not known how CNS trauma affects the expression and activation of RhoA. Here we detect GTP-bound RhoA in spinal cord homogenates and report that spina...
Autores principales: | Dubreuil, Catherine I., Winton, Matthew J., McKerracher, Lisa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172802/ https://www.ncbi.nlm.nih.gov/pubmed/12860969 http://dx.doi.org/10.1083/jcb.200301080 |
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