QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

The 6-O sulfation states of cell surface heparan sulfate proteoglycans (HSPGs) are dynamically regulated to control the growth and specification of embryonic progenitor lineages. However, mechanisms for regulation of HSPG sulfation have been unknown. Here, we report on the biochemical and Wnt signal...

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Detalles Bibliográficos
Autores principales: Ai, Xingbin, Do, Anh-Tri, Lozynska, Olga, Kusche-Gullberg, Marion, Lindahl, Ulf, Emerson, Charles P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172803/
https://www.ncbi.nlm.nih.gov/pubmed/12860968
http://dx.doi.org/10.1083/jcb.200212083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172803/
https://www.ncbi.nlm.nih.gov/pubmed/12860968
http://dx.doi.org/10.1083/jcb.200212083

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