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Homer 2 tunes G protein–coupled receptors stimulus intensity by regulating RGS proteins and PLCβ GAP activities
Homers are scaffolding proteins that bind G protein–coupled receptors (GPCRs), inositol 1,4,5-triphosphate (IP(3)) receptors (IP(3)Rs), ryanodine receptors, and TRP channels. However, their role in Ca(2+) signaling in vivo is not known. Characterization of Ca(2+) signaling in pancreatic acinar cells...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172804/ https://www.ncbi.nlm.nih.gov/pubmed/12860966 http://dx.doi.org/10.1083/jcb.200210109 |